Italian American organization UNICO National is not happy with Take-Two Interactive (or rather, Illusion Softworks') portrayal of Italians in Mafia II, according to Gamasutra. Although UNICO president Andre DiMino hasn't actually played the game (it comes out August 24) he still finds the game's portrayal of Italian Americans reprehensible, calling it a "pile of racist nonsense."
DiMino apparently wrote a strongly worded letter to Take-Two chairman Strauss Zelnick asking for a meeting and informing him that he found offensive the way Mafia II delivers a "denigrating stereotype of organized crime being the exclusive domain of Italians and Italian-Americans." Of course, as I mentioned earlier, he hasn't actually played the game.
Here's a bit more from DiMino:
"Take Two is directly, blatantly and unfairly discriminating and demeaning one group to the exclusion of all others. We are demanding they halt release of the game and cleanse it of all references to Italians and Italian-Americans."
Take-Two chairman Strauss Zelnick responded to UNICO by saying that this particular subject matter "has been featured in movies, television shows and novels" for decades. He also added that "neither UNICO nor any other organization purporting to represent Italian-Americans has seen or played Mafia II."