How Gaming Helped AIDS Researchers

September 19, 2011 -

A research paper published Sunday by the journal Nature Structural & Molecular Biology details how the online game Foldit successfully mapped a protein-cutting enzyme from a particular AIDS-like virus found in rhesus monkeys. This enzyme apparently helps the virus spread and to counteract it, its exact molecular structure had to be mapped. This task had been impossible until crowd sourcing came along.

University of Washington chemist Firas Khatib and computer scientist Seth Cooper handled the Foldit program's design and implementation. In a statement issued to the press, Cooper said that people are what truly made the difference in solving this monumental problem.

"People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans."

Khatib spoke with Seattle Weekly about the project last night, saying that this breakthrough was "huge" for science more than for aids because it could prove to be helpful to researchers throughout the world who could use the extra help with complex problems.

"This is the first case that were aware of where online gamers solved a scientific problem that hadn't been able to be cracked by all scientific methods developed," Khatib says. "My big hope is that other scientists with challenging problems they can't solve and have been banging their heads over for years will come to us and say 'can you help?'"

Khatib says that Foldit's success comes mostly from being an online competitive game. The game has around 236,000 registered players since it launched in 2008. By putting real-time scores and rankings that change based on how well-designed players make their molecular structures, the program takes advantage of the competitive nature of gaming to accomplish something real.

"If we had just posted it as 'hey, can you help us?' I think we would have gotten a few volunteers and some would have stuck around," Khatib says. "But the fact that there is this competitive aspect, that unleashes a lot more motivation."

The next step, says researchers, is for Foldit players to create new genetic structures related to the Flu virus.

"We want to have players design a protein that will inhibit the flu virus," Khatib says. "This is just the start."

Source: Seattle Weekly


 
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Matthew Wilsonfirst, that crap is wrong. second, isnt this the 3rd time he has quit?08/22/2014 - 12:11pm
Zenhttp://levelsave.com/phil-fish-polytron-doxxed-phil-fish-quits-gaming-sells-fez-polytron/ , https://pbs.twimg.com/media/Bvnhvz5IIAAAVc5.png:large08/22/2014 - 12:03pm
ZenHere are some links to the story and images. http://playeressence.com/polytron-and-phil-fish-hacked-tons-of-personal-info-leaked/ , https://pbs.twimg.com/media/Bvnx8sQCIAAwumB.jpg:large , https://pbs.twimg.com/media/Bvnj_zmCUAAlYWm.jpg:large08/22/2014 - 12:02pm
ZenSo...Phil Fish was apparently hacked on both his Twitter and the Polytron site along with all of his personal information has been given out in a zip file. He has since closed his Twitter and stated that Polytron and the Fez IP are for sale. He wants out.08/22/2014 - 12:01pm
Papa MidnightThe Verge says the sequel to Flappy Bird is nearly impossible. http://www.theverge.com/2014/8/21/6053297/swing-copters-flappy-bird-sequel08/21/2014 - 12:22pm
SleakerPC-Gamer wrote an article on what's going on with the Minecraft stuff: http://www.pcgamer.com/2014/08/21/minecraft-bukkit-team-lead-tries-to-end-development-but-mojang-steps-in/08/21/2014 - 11:55am
SleakerEVE had a high-profile ban today: http://massively.joystiq.com/2014/08/20/eve-online-lottery-site-somer-blink-shutting-down/#continued08/21/2014 - 10:26am
SleakerBut where have all the Ethics gone?08/21/2014 - 9:08am
Sleaker@EZK - one of the bigger things is that since Mojang has owned Bukkit for 2 years now, people contributing to the project have basically been doing work for them pro-bono. On top of never formalizing support. They hid the fact probably to prevent support08/21/2014 - 9:07am
SleakerIf you've played on a server with mods/plugins, you've almost for sure played on a Bukkit-based server.08/21/2014 - 8:56am
SleakerHere's Bukkit's explanation attempt at shutting down due to EULA changes: http://forums.bukkit.org/threads/bukkit-its-time-to-say.305106/08/21/2014 - 8:55am
SleakerEZK - it's the largest server mod for MC, in actuality without it minecraft for sure would not have been as popular (#1 game now).08/21/2014 - 8:54am
SleakerTo the point that it seems they have completely lost what it means to be for-community, and having transparency. Along with dumping restrictive EULA's onto people.08/21/2014 - 8:53am
E. Zachary KnightWhat is Bukkit and why should I care?08/21/2014 - 8:53am
SleakerMinecraft community exploded again today. Apparently Mojang owns all of Bukkit, and never put out a statement saying as such 2 years ago when they acquired them. I have to say, their transition from indie has been rough.08/21/2014 - 8:52am
james_fudgeThere aren't many left in America08/21/2014 - 1:50am
MechaTama31I sure have. Dorky's barcade in Tacoma, WA.08/20/2014 - 5:56pm
Matthew WilsonI have not been to a arcade in years. I know arcades are still big in japan.08/20/2014 - 5:38pm
Sleaker@AE - Ah no it's called GroundKontrol - I was just referring to it as a Bar-Arcade.08/20/2014 - 4:39pm
Andrew EisenStill looking for confirmation that High Moon Studios (dev behind the PS3/360 versions) isn't working on it.08/20/2014 - 4:38pm
 

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