How Gaming Helped AIDS Researchers

September 19, 2011 -

A research paper published Sunday by the journal Nature Structural & Molecular Biology details how the online game Foldit successfully mapped a protein-cutting enzyme from a particular AIDS-like virus found in rhesus monkeys. This enzyme apparently helps the virus spread and to counteract it, its exact molecular structure had to be mapped. This task had been impossible until crowd sourcing came along.

University of Washington chemist Firas Khatib and computer scientist Seth Cooper handled the Foldit program's design and implementation. In a statement issued to the press, Cooper said that people are what truly made the difference in solving this monumental problem.

"People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans."

Khatib spoke with Seattle Weekly about the project last night, saying that this breakthrough was "huge" for science more than for aids because it could prove to be helpful to researchers throughout the world who could use the extra help with complex problems.

"This is the first case that were aware of where online gamers solved a scientific problem that hadn't been able to be cracked by all scientific methods developed," Khatib says. "My big hope is that other scientists with challenging problems they can't solve and have been banging their heads over for years will come to us and say 'can you help?'"

Khatib says that Foldit's success comes mostly from being an online competitive game. The game has around 236,000 registered players since it launched in 2008. By putting real-time scores and rankings that change based on how well-designed players make their molecular structures, the program takes advantage of the competitive nature of gaming to accomplish something real.

"If we had just posted it as 'hey, can you help us?' I think we would have gotten a few volunteers and some would have stuck around," Khatib says. "But the fact that there is this competitive aspect, that unleashes a lot more motivation."

The next step, says researchers, is for Foldit players to create new genetic structures related to the Flu virus.

"We want to have players design a protein that will inhibit the flu virus," Khatib says. "This is just the start."

Source: Seattle Weekly


 
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ZippyDSMleeuuuhhhggg in other news been sick since last night.....uuhggg.....I iwsh it did not hurt so much when my tummy wants to leave my body..02/28/2015 - 11:39pm
ZippyDSMleeBrings me to the Q why alt costumes would be needed in competition anyway... http://www.eventhubs.com/news/2015/feb/28/dead-or-alive-community-aims-ban-over-120-overly-sexualized-costumes-dead-or-alive-5-last-round/02/28/2015 - 11:36pm
MonteThough from a business side, i would agree with the article. While it would be smarter for developers to slow down, you can't expect EA, Activision or ubisoft to do something like that. Nintnedo's gotta get the third party back.02/28/2015 - 4:36pm
MonteThough it does also help that nintendo's more colorful style is a lot less reliant on graphics than more realistic games. Wind Waker is over 10 years old and still looks good for its age.02/28/2015 - 4:33pm
MonteWith the Wii, nintnedo had the right idea. Hold back on shiny graphics and focus on the gameplay experience. Unfortunatly everyone else keeps pushing for newer graphics and it matters less and less each generation. I can barely notice the difference02/28/2015 - 4:29pm
MonteON third party developers; i kinda think they should slow down to nintendo's pace. They bemoan the rising costs of AAA gaming, but then constantly push for the best graphics which is makes up a lot of those costs. Be easier to afford if they held back02/28/2015 - 4:27pm
Matthew Wilsonhttp://www.forbes.com/sites/insertcoin/2015/02/28/the-world-is-nintendos-if-only-theyd-take-it/ I think this is a interesting op-ed, but yeah it kind of is stating the obvious.02/28/2015 - 2:52pm
prh99The government probably doesn't need an app, but I was think more along the lines of a company that was going to sell the collected info. “If you're not paying for the product, you are the product” sometimes even if you pay.02/28/2015 - 1:50pm
E. Zachary KnightWhat better way for the government to keep track of you than to get you to install an app that lets you insult the government.02/28/2015 - 11:03am
prh99No, but I looked it up and it's basically spyware. Their privacy policy says their apps tracks among other things your location and browsing habits via cookies.02/28/2015 - 8:20am
Ryan RardinHas anyone here heard of an app called iCitizen? It's basically Yelp for politicians.02/28/2015 - 5:16am
Andrew EisenAh, not linked in the way you (and everyone else) want and expect. That's true.02/27/2015 - 10:06pm
Matthew Wilsonthey are not linked in a way that tracks purchases though. the fact that they have to send a code for the other system shows that they are not linked in the way it counts.02/27/2015 - 9:39pm
Andrew EisenAccounts are already linked. Have been for quite a while. Also, Mario vs. Donkey Kong was announced as a cross-buy title during last January's Nintendo Direct.02/27/2015 - 9:25pm
Matthew Wilsonhttp://www.vg247.com/20…/…/27/olli-olli-3ds-wii-u-cross-buy/ I wounder if this is a sign that Nintendo may finally link accounts across the 3ds/wiiu in the near future.02/27/2015 - 9:18pm
prh99http://www.romanoriginals.co.uk/invt/70931?colour=Blue The dress does comes in white and blue but both have black lace and a sheer back top, I don't see gold or brown. 02/27/2015 - 8:54pm
ZippyDSMleeDungeons was a so bad so good game to me so I been keeping up with its sequel which will more of a Dungeon Keeper clone. As for pre order out of 7 preorders I was not burnt by 2... Add my contempt of most of modern game design.Ya I have all kinds of hurt.02/27/2015 - 8:40pm
MechaTama31I don't even want to know...02/27/2015 - 8:22pm
ZippyDSMleeFun? I can do fun…. I think LOL. Dungeons 2 is on preorder but not via steam... >> Hell I am breaking all kinds of personal butthurt rules to even THINK about pre order...02/27/2015 - 8:12pm
E. Zachary KnightHad some fun discussions about that dumb dress on Facebook. I opened the original picture in GIMP and sampled the colors and determined them to be Blue and Gold. People still say I am wrong.02/27/2015 - 7:41pm
 

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