Gamers help scientists study genetics and disease

December 7, 2011 -

Scientists are using a web-based video game to entice gamers to assist them in the study of genetic diseases.

The game, called Phylo and launched in November 2010, allows players to rearrange colored blocks that represent human DNA. Scientists have been studying the results and will release their findings soon. 

The game has more than 17,000 registered users and more than 350,000 solutions have been found to alignment sequence problems. According to an article on MedicalXpress.com, the game was created by Dr. Jérôme Waldispuhl and his students at McGill School of Computer Science:

Waldispuhl and his students came up with the idea of using a to solve the problem of DNA multiple sequence alignment because it is a task that is difficult for computers to do well. "There are some calculations that the human brain does more efficiently than any computer can. Recognizing and sorting visual patterns fall in that category," explained Waldispuhl. "Computers are best at handling large amounts of messy data, but where we require high accuracy, we need humans. In this case, the genomes we're analyzing have already been pre-aligned by computers, but there are parts of it that are misaligned. Our goal is to identify these parts and transform the task of aligning them into a puzzle people will want to sort out."

Waldisphul also said:

"Phylo has contributed to improving our understanding of the regulation of 521 genes involved in a variety of diseases. It also confirms that difficult computational problems can be embedded in a casual game that can easily be played by people without any scientific training. What we're doing here is different from classical citizen science approaches. We aren't substituting humans for computers or asking them to compete with the machines. They are working together. It's a synergy of humans and machines that helps to solve one of the most fundamental biological problems."

If you want to give scientists a helping hand, play the game.


Comments

Re: Gamers help scientists study genetics and disease

Stuff like Folding @home are good additions I think its great to leave your system on once a week to help out

 
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Mattsworknamei I hope there is, I love that series.04/25/2015 - 5:59pm
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Mattsworknameof From softwares recent games, bloodborne is the best work they have done yet, though they really need to get to work on armored core 604/25/2015 - 5:10pm
Matthew WilsonLost Kingdoms came out in 2002 this day. I played that game. I did not relize it was made by From Software. Lost Kingdoms was a good unique hard game.04/25/2015 - 4:56pm
MattsworknameOff topic, but, who heres playing Bloodborne, and if so, is it mercillesly murdering you every chance it gets?04/25/2015 - 7:35am
Matthew WilsonI think its a good article, and devs can take some lessons from life is strange.04/24/2015 - 10:24pm
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Matthew Wilson@AE my bad there is nothing I can do about that.04/24/2015 - 10:21pm
Andrew EisenLooks like the spoiler is right there in the URL.04/24/2015 - 10:20pm
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Andrew EisenWell, that is indeed crappy and nonsensical.04/24/2015 - 3:45pm
Matthew Wilsonshe got attacked for saying that she personaly has not experienced the harassment some other female devs have, and she got acused of defending GG and ignoring harassment. she ended up getting dog piled because of it.04/24/2015 - 3:43pm
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