A Siliconera report suggests that the next Dead Rising game is already in the works and will have a serious social issue in the context of its story. Capcom is not commenting on the details of the report, save to say that they have not announced anything about the next Dead Rising game. If the report is true, the next paragraph may contain spoilers that will make you sad in your soul. If you think spoilers are bad, then you might want to stop reading right now.
According to the report the next game will take place in a fictional California town called "Los Perdidos" on the U.S. Mexican border, which has been closed down due to a zombie outbreak. The protagonist for "Dead Rising 3" will be an auto mechanic named Rick, who is trying to restore a small airplane to escape the town. The game's storyline will follow Rick's antics while scrounging for airplane parts and will contain "an undercurrent of themes about illegal immigration."
It's an interesting idea, but Capcom has had its fair share of controversy when it comes to portraying race in its games - Resident Evil 5 comes to mind...